Several medications containing Losartan are being recalled. (Black Press file photo)

Potential ‘human carcinogen’ leads to recall of Losartan-containing drugs

Health Canada is advising that there is no immediate risk to patients taking these medications

Multiple high blood pressure medications containing Losartan are being voluntarily recalled due to a “potentially human carcinogen,” Health Canada says.

Teva Canada, Apotex Inc., Pharmascience Inc,m and Pro Doc Limitée are recalling lots of Losartan-containing drugs because of the potential for a nitrosamine impurity, N-Nitroso-N-methyl-4-aminobutyric acid (NMBA) – a potential human carcinogen meaning that long-term exposure could increase the potential risk of cancer.

As with previous recalls involving nitrosamine impurities, Health Canada is advising that there is no immediate risk to patients taking these medications since the potential risk of cancer is with long-term exposure to the impurities.

“Patients should not stop taking their medication unless advised to do so by their healthcare provider,” Health Canada says.

Teva Canada is voluntarily recalling two lots of combination Losartan/hydrochlorothiazide (HCTZ) tablets after testing of one lot identified levels of NMBA above what is considered reasonably safe if the drug were taken over a lifetime. Apotex Inc., Pharmascience Inc., and Pro Doc Limitée are voluntarily recalling multiple lots of Losartan-containing products as a precaution.

The Losartan active pharmaceutical ingredient (API) in all of the recalled products is manufactured by Hetero Labs Ltd. Unit 1, in India. These recalls represent all lots of drugs distributed in Canada that contain Losartan API manufactured at Hetero Labs Ltd. Unit 1.

Related: Children’s strawberry-flavoured medicines recalled due to faulty safety cap

Related: Brewer’s yeast recall for peanut allergies

Losartan is an angiotensin receptor blocker (ARB) drug, also known as a “sartan.” Sartans are a class of drugs used to treat patients with high blood pressure to help prevent heart attacks and stroke. They are also used in patients who have had heart failure or a recent heart attack. There have been multiple recalls of products containing another sartan, valsartan, in Canada and internationally since July 2018 because of nitrosamine impurities (see links below for more information).

There are alternative products currently available on the Canadian market.

Health Canada continues to monitor the supply situation. Health Canada encourages Canadians to visit drugshortagescanada.ca for information on drug shortages and discontinuances. Patients with questions or concerns about any drug they are taking, including on what to do if that drug is not readily available, should speak to their healthcare professional.

For a list of affected products, visit healthycanadians.gc.ca.


@VernonNews
newstips@vernonmorningstar.com

Like us on Facebook and follow us on Twitter.

Get local stories you won't find anywhere else right to your inbox.
Sign up here

Just Posted

Ride-hailing licence expected in Maple Ridge by April 1

Regional licence now on council agenda

Maple Ridge RCMP continue search for Atefeh Jadidian

The police released a new photo showing the missing woman walking east on Dewdney Trunk Road

Street drug deaths drop by half in Maple Ridge

City last on list of 15 with highest number of fatalities

COMMUNITY NETWORK: Weekend wellness event connects Indigenous with resources

Culture can be a medicine for Aboriginal people, as columnist Ginna Berg explains ahead of Saturday

Dragon boating changes lives for Spirit Abreast paddlers

The Cultus Lake based team is looking to fill a boat with breast cancer survivors and supporters.

Cheslatta Carrier Nation and Rio Tinto sign a historic agreement

Co-operation crucial to stem dropping Nechako Reservoir level

Hundreds of B.C. firefighters ‘climb the wall’ for BC Lung Association

The charity fundraiser saw participants climbing up 48 storeys

Stories of sexual assault at B.C. tree planting camps ‘shocking but not surprising:’ advocate

Contractors’ association is working with trainers to create respectful culture

Notorious B.C. fugitive to be extradited from California on murder charge

Brandon Nathan Teixeira submitted to extradition during court proceedings Thursday in Sacramento

Canada prepared to monitor for community spread of COVID-19: Tam

The U.S. confirmed one case of the new coronavirus, or COVID-19, in California Thursday

Decade-long health care battle draws to a close today in B.C.

Dr. Brian Day began his battle a decade ago against the B.C. government

Most Read